Ovarian Malignancy : Routine Investigations & Specific Investigations :

Routine Investigations :

1.Hemogram , Blood group;

2.Liver function tests;

3.Kidney function tests;

4.Fasting and postprandial blood sugars;

5.Urine - routine/microscopy;

6.X-Ray chest (PA view);

7.ECG.

Specific Investigations:

1.Tumor markers

CA-125 >35 UI/l in epithelial tumors;

CEA

AFP - Increased in embryonal carcinoma and endodermal sinus tumor;

HCG - Increased in choriocarcinoma;

PLAP,LDH - Increased in dysgerminoma

Inhibin B - Increased in granulose cell tumor

2.USG and USG guided FNAC;

3.Contrast enhanced CT scan;

4.Intravenous pyelography (IVP);

5.Barium enema - To rule out carcinoma of colon;

6.Colonoscopy , upper GI endoscopy to rule out Krukemberg tumor ;

7.Cystoscopy if spread to bladder is suspected;

8.Endometrial biopsy , endocervical curettage -if history of postmenopausal bleeding or menstrual irregularities;

9.Ascitic fluid tap for biochemistry , cytology for confirmation of tissue diagnosis.